PKM2-IN-10 (Compound 16) is a PKM2 inhibitor. PKM2-IN-10 inhibits the proliferation of A549 and HCC1833 cell lines with IC50 of 3.36 µM and 9.20 µM, respectively. PKM2-IN-10 exhibits antitumor activity in human non-small cell lung cancer (NSCLC) and mouse lung adenocarcinoma models. PKM2-IN-10 can be used in lung cancer research[1].
Molecular Weight:
413.37
Formula:
C21H15F4N5
Target:
Pyruvate Kinase
Application Notes:
MCE Product type: Reference compound
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