CDK9/HDAC1/HDAC3-IN-1, CAS [[2197029-81-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-172891
Supplier Catalog Number:
HY-172891
Alternative Catalog Number:
MCE-HY-172891-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
CDK9/HDAC1/HDAC3-IN-1 is dual-functional inhibitor of CDK9 and HDAC. CDK9/HDAC1/HDAC3-IN-1 inhibits the protein activity of CDK9/HDAC/HDAC3 with IC50 s of 0.17 µM, 1.73 µM and 1.11 µM for CDK9, HDAC1, and HDAC3, respectively. CDK9/HDAC1/HDAC3-IN-1 inhibits cancer cells by inducing cell apoptosis and cell cycle arrest in the G2/M phase, as well as tumor growth in a murine TNBC MDA-MB-231 xenograft model. CDK9/HDAC1/HDAC3-IN-1 has a broad-spectrum anti-cancer activity, such as breast cancer, cervical cancer, and liver cancer[1].
Molecular Weight:
470.55
CAS Number:
[2197029-81-3]
Formula:
C24H22N8OS
Target:
Apoptosis,CDK,HDAC
Application Notes:
MCE Product type: Reference compound
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