ACLY-IN-1 is an orally active ACLY inhibitor. ACLY-IN-1 exhibits potent ACLY inhibitory activity (IC50 = 8.3 nM) and high binding affinity (KD = 72.0 nM) to ACLY. ACLY-IN-1 demonstrates good pharmacokinetic profiles and a potent in vivo hypolipidemic effect[1].
Molecular Weight:
529.74
CAS Number:
[2897695-26-8]
Formula:
C20H12BrClF2N2O4S
Target:
ATP Citrate Lyase
Application Notes:
MCE Product type: Reference compound
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