PDEdelta/NAMPT IN-1, CAS [[2976498-55-0]] Preis auf Anfrage

Product Overview

• Article Name: PDEdelta/NAMPT IN-1, CAS [[2976498-55-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-172919
• Supplier Catalog Number: HY-172919
• Alternative Catalog Number: MCE-HY-172919-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PDEdelta/NAMPT IN-1 (Compound 17d) is a dual inhibitor targeting phosphodiesterase 6 (PDE6) (KD=0.410 nM) and nicotinamide phosphoribosyl transferase (NAMPT) (IC50=2.21 nM). PDEdelta/NAMPT IN-1 blocks KRAS-related signal transduction and interferes with the synthesis of nicotinamide adenine dinucleotide (NAD+), inducing apoptosis in KRAS mutant pancreatic cancer cells. PDEdelta/NAMPT IN-1 is promising for research of KRAS mutant pancreatic cancer[1].

Product Properties

• Molecular Weight: 494.61
• CAS Number: [2976498-55-0]
• Formula: C26H30N4O4S
• Target: Apoptosis,NAMPT,Phosphodiesterase (PDE)

Application Notes

• Application Notes: MCE Product type: Reference compound