DEG-35 is a CRBN-dependent, dual IKZF2 and CK1alpha molecule glue degrader, with DC50 values of 1.4 nM and 4.4 nM for CK1alpha and IKZF2, respectively. DEG-35 activates the p53 apoptosis pathway. DEG-35 can be used in the research for Acute Myeloid Leukemia (AML)[1].
Molecular Weight:
443.45
Purity:
98.88
CAS Number:
[2734910-37-1]
Formula:
C25H21N3O5
Target:
Casein Kinase,IKZF Family,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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