SD-2301 is a selective STAT3 PROTAC degrader. SD-2301 induces STAT3 degradation without affecting the protein levels of other STAT family members (STAT1, STAT2, STAT4, STAT5, STAT6). SD-2301 exerts anti-tumor effects in B16F10-bearing mice. SD-2301 can be used for the study of cancer. (Pink: STAT3 ligand (HY-172947), Blue: VHL Ligand (HY-172948), Black: Linker (HY-W577012), VHL ligand-linker conjugate (HY-172949))[1].
Molecular Weight:
1366.50
CAS Number:
[3054116-24-1]
Formula:
C64H80N13O15PS2
Target:
PROTACs,STAT
Application Notes:
MCE Product type: Reference compound
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