KRASG12C IN-15, CAS [[2768868-14-8]] Preis auf Anfrage

Product Overview

• Article Name: KRASG12C IN-15, CAS [[2768868-14-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-173047
• Supplier Catalog Number: HY-173047
• Alternative Catalog Number: MCE-HY-173047-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

KRASG12C IN-15 (Compound 21) is the orally active inhibitor for KRASG12C, and inhibits SOS1-mediated GDP/GTP exchange with an IC50 of 19 nM. KRASG12C IN-15 inhibits the phosphorylation of ERK with IC50 of 0.051 µM. KRASG12C IN-15 inhibits the cell viability of KRASG12C mutated MIA PaCa-2 with IC50 of 0.023 µM. KRASG12C IN-15 exhibits antitumor effect in MIA PaCa-2 xenograft mouse models[1].

Product Properties

• Molecular Weight: 497.60
• CAS Number: [2768868-14-8]
• Formula: C31H32FN3O2
• Target: ERK,Ras

Application Notes

• Application Notes: MCE Product type: Reference compound