TLR8 antagonist-1 (Compound 10) is a selective TLR8 antagonist. TLR8 antagonist-1 can inhibit TLR8-mediated inflammation and signaling pathways, reduce the recruitment of MyD88, and inhibit the NF-kappaB and IRF pathways. TLR8 antagonist-1 has anti-inflammatory activity[1].
Molecular Weight:
387.47
Purity:
99.95
CAS Number:
[1111460-83-3]
Formula:
C21H29N3O4
Target:
MyD88,NF-kappaB,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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