Anti-inflammatory agent 97 (Compound 1l), an anti-inflammation agent, can also inhibit oxidative stress. Anti-inflammatory agent 97 can inhibit the colonic shortening and suppress inflammatory symptoms of the colonic tissue in the DSS (HY-116282C)-induced ulcerative colitis mice model. Anti-inflammatory agent 97 can regulate the inflammation-related TLR4/NF-kappaB signaling pathway and the oxidative stress-related Nrf2/HO-1 signaling pathway[1].
Molecular Weight:
462.59
Formula:
C27H37F3N2O
Target:
NF-kappaB,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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