PROTAC KDM4 degrader-1 is a KDM4 PROTAC degrader that degrades KDM4A-C with DC50 values of 37.53, 39.93, and 49.41 nM, respectively, while sparing KDM4D. PROTAC KDM4 degrader-1 induces cell cycle arrest, apoptosis and antiproliferative activity in esophageal cancer cells. PROTAC KDM4 degrader-1 can be used for the research of esophageal cancer[1].
Molecular Weight:
1002.27
CAS Number:
[3102423-10-6]
Formula:
C56H71N7O8S
Target:
Apoptosis,Histone Demethylase,PROTACs
Application Notes:
MCE Product type: Reference compound
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