EGFR/BRAFV600E-IN-4 (Compound 10f) is a dual EGFR and BRAFV600E inhibitor with IC50 values of 61 nM and 43 nM, respectively. EGFR/BRAFV600E-IN-4 arrests cell cycle, induces apoptosis in both early and late stages and inhibits cancer cells growth in vitro, and has a broad anticancer activity[1].
Molecular Weight:
384.45
Formula:
C22H16N4OS
Target:
Apoptosis,EGFR,Raf
Application Notes:
MCE Product type: Reference compound
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