Antitumor agent-200, CAS [[3046118-64-0]] Preis auf Anfrage

Product Overview

• Article Name: Antitumor agent-200, CAS [[3046118-64-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-173182
• Supplier Catalog Number: HY-173182
• Alternative Catalog Number: MCE-HY-173182-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Antitumor agent-200 (Compound 2g) is a microtubule synthesis inhibitor. By binding to the colchicine site of tubulin, it causes G2/M cell cycle arrest and generates reactive oxygen species (ROS). Antitumor agent-200 exhibits significant inhibitory activity against MCF7/ADR and KBV200 cell lines with overexpression of P-glycoprotein (P-gp), with drug resistance indices (DRI) of 0.83 and 0.58 respectively. In the MCF-7 xenograft model, Antitumor agent-200 (25 mg/kg, intraperitoneal injection) can achieve a tumor growth inhibition rate of 57.2%. Antitumor agent-200 can be used in the research of the anti-cancer field[1].

Product Properties

• Molecular Weight: 423.34
• CAS Number: [3046118-64-0]
• Formula: C19H21FN2O3Se
• Target: Microtubule/Tubulin,P-glycoprotein

Application Notes

• Application Notes: MCE Product type: Reference compound