Keap1-Nrf2-IN-27 (compound 1C) is a inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) with KD2 value of 0.119 µM. Keap1-Nrf2-IN-27 suppresses the expression of pro-inflammatory cytokine TNF-alpha and IL-6 in the LPS-induced RAW264.7 cell model[1].
Molecular Weight:
695.72
Formula:
C31H29N5O10S2
Target:
Keap1-Nrf2
Application Notes:
MCE Product type: Reference compound
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