PLK1-IN-13, CAS [[3038489-48-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-173212
Supplier Catalog Number:
HY-173212
Alternative Catalog Number:
MCE-HY-173212-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PLK1-IN-13 is a selective and orally active PLK1 inhibitor (IC50: 0.27 nM). PLK1-IN-13 also inhibits PLK2 (IC50: 12.72 nM) and PLK3 (IC50: 4.12 nM). PLK1-IN-13 arrests cell at G2 phase, induces apoptosis and down-regulates the transcription of the proliferation-related oncogene c-MYC. PLK1-IN-13 inhibits tumor growth, and can be used for research of acute myeloid leukemia (AML)[1].
Molecular Weight:
577.74
CAS Number:
[3038489-48-1]
Formula:
C29H39N9O2S
Target:
Apoptosis,c-Myc,Polo-like Kinase (PLK)
Application Notes:
MCE Product type: Reference compound
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