BACE1-IN-15 (Compound 72) is a selective inhibitor of beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1) with oral activity and the ability to penetrate the blood-brain barrier. Its IC50 value is 121.65 nM (the IC50 value for BACE-2 is 480.92 nM). BACE1-IN-15 can be used in the research of the Alzheimers disease field[1]
Molecular Weight:
335.33
Formula:
C15H11F2N3O2S
Target:
Beta-secretase
Application Notes:
MCE Product type: Reference compound
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