VEGFR-2-IN-66 (Compound 6) is an orally active VEGFR-2 inhibitor with an IC50 value of 0.509 µM and an IC50 value of 7.48 µM for inhibiting the proliferation of MCF-7 cells. VEGFR-2-IN-66 exerts its anti-cancer activity by arresting the cell cycle, inducing apoptosis, and regulating gene expression, and can be used in the research of the breast cancer field[1].
Molecular Weight:
422.44
Formula:
C20H22N8O3
Target:
Apoptosis,VEGFR
Application Notes:
MCE Product type: Reference compound
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