PLK1-IN-14 (Compound Hit-4) is a selective PLK1 inhibitor. It has an IC50 of 22.61 pM against PLK1 and an IC50 of 0.09 nM for inhibiting the proliferation of DU - 145 prostate cancer cells. PLK1-IN-14 can be used in the research of prostate cancer[1].
Molecular Weight:
802.92
Formula:
C41H55F5N8O3
Target:
Polo-like Kinase (PLK)
Application Notes:
MCE Product type: Reference compound
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