YN14-H Preis auf Anfrage
Catalog Number:
MCE-HY-173250
| Article Name: |
YN14-H Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-173250 |
| Supplier Catalog Number: |
HY-173250 |
| Alternative Catalog Number: |
MCE-HY-173250-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| YN14-H is a PROTAC degrader targeting KRASG12C. YN14-H inhibits cell growth in NCI-H358 and MIA PaCa-2 cells (IC50 values of 0.042, 0.021 µM, DC50 values of 28.9, 18.1 nM, respectively). YN14-H significantly induces apoptosis and inhibits migration. YN14-H demonstrates favorable pharmacokinetic properties and excellent antitumor activity in vivo. (Structure Note: Pink: target protein ligand (HY-173252), Blue: E3 ligase ligand (HY-125905), Black: linker (HY-Y0840), E3 ligase ligand + linker (HY-173253)[1]. |
| Molecular Weight: |
1230.44 |
| Formula: |
C65H78F3N11O8S |
| Target: |
Apoptosis,PROTACs,Ras |
| Application Notes: |
MCE Product type: Reference compound |
