TO-1187 is a selective HDAC6 PROTAC degrader (DC50: 5.81 nM). TO-1187 promotes the ubiquitination and degradation of HDAC6 and can be used in the study of hematological malignancies and solid tumors (Pink: HDAC6 ligand (HY-173386), Blue: CRBN ligase ligand (HY-41547), Black: linker (HY-140212))[1].
Molecular Weight:
681.70
Formula:
C34H35N9O7
Target:
HDAC,PROTACs
Application Notes:
MCE Product type: Reference compound
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