Tau ligand-1 (Compound 75) is a ligand for aggregated tau protein that can penetrate the blood-brain barrier[1]. In tissues from patients with Alzheimers disease, progressive supranuclear palsy, corticobasal degeneration, and Picks disease, Tau ligand-1 exhibits high affinity for aggregated tau protein, with equilibrium dissociation constant (KD) values ranging from 1 to 3.8 nM[1]. Tau ligand-1 can serve as a potential positron emission tomography (PET) tracer and holds promise for application in positron emission tomography imaging studies of tau-related diseases in the central nervous system[1].
Molecular Weight:
297.33
Purity:
99.47
CAS Number:
[3063166-64-0]
Formula:
C17H16FN3O
Target:
Tau Protein
Application Notes:
MCE Product type: Reference compound
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