ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM[1]. In an experimental mouse model of liver injury induced by Acetaminophen (HY-66005), ASK1-IN-8 can significantly reduce the plasma alanine transaminase (ALT) level, protecting the liver[1]. ASK1-IN-8 can be used in research related to liver diseases[1].
Molecular Weight:
488.58
CAS Number:
[2570985-89-4]
Formula:
C26H32N8O2
Target:
ASK1
Application Notes:
MCE Product type: Reference compound
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