Anti-MRSA agent 25 (Compound 10c) is an antibacterial agent with a MIC of 0.25 µg/mL against methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 25 exerts its antibacterial activity by inhibiting biofilm formation, disrupting the cell wall (interacting with peptidoglycan and lipoteichoic acids), acting on the cell membrane (causing depolarization, increasing permeability, and disrupting integrity), reducing metabolic activity, interfering with cellular redox homeostasis, and binding to DNA. Anti-MRSA agent 25 is expected to be used in the research of the anti-infection field[1].
Molecular Weight:
772.54
Formula:
C35H42I2N4
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound1
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