PDE10A-IN-5 (Compound A30) is an inhibitor of phosphodiesterase 10A (PDE10A) with oral activity, and its IC50 value is 3.5 nM. PDE10A-IN-5 exerts the activity of inhibiting pulmonary vascular remodeling by inhibiting PDE10A and activating the cyclic adenosine monophosphate (cAMP)-associated signaling pathway, and can be used for research in the field of pulmonary arterial hypertension[1].
Molecular Weight:
514.62
Formula:
C29H34N6O3
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound1
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