Anti-inflammatory agent 100 (Compound (+)-4S-23) is an anti-inflammatory agent. Anti-inflammatory agent 100 inhibits MAPK and NF-kappaB signaling, and also inhibits NF-kappaB pathway by suppressing the phosphorylation of IkappaB-alpha and blocking nuclear translocation of phosphorylated p65. Anti-inflammatory agent 100 inhibits NO production (IC50: 0.5 µM) and TNF-alpha, IL-6, IL-1beta secretion[1].
Molecular Weight:
389.40
Formula:
C22H19N3O4
Target:
ERK,JNK,NF-kappaB,p38 MAPK
Application Notes:
MCE Product type: Reference compound1
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