FAK-IN-26 is a BBB-penetrable Focal Adhesion Kinase (FAK) inhibitor (IC50: 0.87 nM). FAK-IN-26 significantly suppresses tumor cell viability, cancer stem cell activity, and cell migration in A549 and SKOV-3 cell lines. FAK-IN-26 has potent anti-cancer activity in A549 and SKOV-3 tumor mice models with tumor inhibition rates of 59.15 % and 57.9 %[1].
Molecular Weight:
460.30
CAS Number:
[2801785-12-4]
Formula:
C20H19BrFN5O2
Target:
FAK
Application Notes:
MCE Product type: Reference compound
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