JNJ-9676 is an orally active inhibitor of membrane (M) protein. JNJ-9676 has in vitro antiviral activity against SARS-CoV-2, SARS-CoV, and sarbecovirus from bats and pangolins. JNJ-9676 inhibits viral assembly by stabilizing the conformational changes of the M protein dimer, preventing the release of infectious viruses. JNJ-9676 has significant antiviral effects and can be used in research on the prevention and treatment of coronavirus infections[1].
Molecular Weight:
497.50
Purity:
99.74
CAS Number:
[3026520-19-1]
Formula:
C28H21F2N5O2
Target:
DNA/RNA Synthesis,SARS-CoV
Application Notes:
MCE Product type: Reference compound
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