JNJ-9676 is an orally active Coronavirus M protein inhibitor and selective Sarbecovirus inhibitor. JNJ-9676 binds to the M protein dimer and forces the protein into an alternative conformational state with a compound-induced binding pocket. JNJ-9676 demonstrates in vitro nanomolar antiviral activity against SARS-CoV-2, SARS-CoV and Sarbecovirus strains from bat and pangolin zoonotic origin[1].
Molecular Weight:
497.50
Purity:
99.74
CAS Number:
[3026520-19-1]
Formula:
C28H21F2N5O2
Target:
DNA/RNA Synthesis,SARS-CoV
Application Notes:
MCE Product type: Reference compound
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