PRMT7-IN-2 (A33) is a selective PRMT7 inhibitor with an IC50 of 0.50 µM. PRMT7-IN-2 arrests cell cycle at G0/G1 phase, induces cell apoptosis, and inhibits cell growth in vivo and in vitro. PRMT7-IN-2 decreases the monomethylarginine level of PRMT7, increases expression of epithelial marker (E-cadherin, and reduces expression of mesenchymal markers such as N-cadherin, Vimentin, and ZEB2[1].
Molecular Weight:
473.55
Purity:
98.26
CAS Number:
[3058094-83-7]
Formula:
C25H23N5O3S
Target:
Apoptosis,Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound1
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