PD-L1/HDAC3-IN-1 (PH3) is a dual PD-L1/HDAC3 Inhibitor with IC50 values of 89.4 nM and 107 nM for PD-1/PD-L1 and HDAC3, respectively. PD-L1/HDAC3-IN-1 induces cell apoptosis and arrests cell cycle at G0/G1 phase. PD-L1/HDAC3-IN-1 shows anticancer activity both in vivo and in vitro[1].
Molecular Weight:
446.58
Formula:
C27H34N4O2
Target:
Apoptosis,HDAC,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound1
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