AR antagonist 12, CAS [[2902679-42-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-173559
Supplier Catalog Number:
HY-173559
Alternative Catalog Number:
MCE-HY-173559-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
AR antagonist 12 (compound 20i) is an orally active androgen receptor antagonist wiith IC50 values of 119.3 µM and 98.2 µM for wt-AR and AR-F877L,respectively. AR antagonist 12 induces a dose-dependent and time-dependent reduction in AR, AR-V7, and PSA protein levels. AR antagonist 1 shows anticancer activuty and can be used for the study of Enzalutamide (HY-70002)-resistant Prostate cancer[1].
Molecular Weight:
484.47
CAS Number:
[2902679-42-7]
Formula:
C24H23F3N6O2
Target:
Androgen Receptor
Application Notes:
MCE Product type: Reference compound1
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