DJ-89 (Compound 77) is a potent soluble epoxide hydrolase (sEH) inhibitor with an IC50 value of 0.51 nM . DJ-89 inhibits sEH from hydrolyzing epoxyeicosatrienoic acids (EETs), reducing the production of pro-inflammatory substances. DJ-89 is promising for research of acute and chronic inflammatory diseases (such as rheumatoid arthritis)[1].
Molecular Weight:
495.49
Formula:
C24H28F3N3O5
Target:
Epoxide Hydrolase
Application Notes:
MCE Product type: Reference compound
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