T0080 is a FPR-1 antagonist. T0080 reduces the cell apoptosis, inhibits ROS production and pro-inflammatory cytokines (TNF-alpha and IL-1beta) from plaque macrophages, which attenuates atherosclerotic progression in ApoE-/- mice[1].
Molecular Weight:
457.44
Purity:
99.94
CAS Number:
[2785323-68-2]
Formula:
C24H22F3N3O3
Target:
Apoptosis,Formyl Peptide Receptor (FPR),Interleukin Related,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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