JAK3-IN-17 (Compound X15) is an orally active JAK3 inhibitor (IC50: 14.56 nM). JAK3-IN-17 inhibits the production of IL-2 and IL-6 in a DNCB-induced mouse atopic dermatitis model and exhibits anti-inflammatory activity[1].
Molecular Weight:
358.37
Formula:
C21H15FN4O
Target:
JAK
Application Notes:
MCE Product type: Reference compound1
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