Vicriviroc maleate (SCH-417690 maleate, SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC90s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570).
Molecular Weight:
649.70
Purity:
99.91
CAS Number:
[599179-03-0]
Formula:
C32H42F3N5O6
Target:
CCR,HIV
Application Notes:
MCE Product type: Reference compound1
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