Nisoldipine (BAY-k 5552, Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels. Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity[1][2][7][11].
Molecular Weight:
388.41
Purity:
99.56
CAS Number:
[63675-72-9]
Formula:
C20H24N2O6
Target:
Calcium Channel,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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