SI-W052 is an orally active, brain-penetrant and selective small-molecule inhibitor targeting mTOR and TEX264. SI-W052 activates autophagy by inhibiting mTOR phosphorylation and enhances TEX264 expression to promote ER turnover, suppressing LPS-induced release of inflammatory factors (TNF-alpha, IL-6). SI-W052 is promising for research of Alzheimers disease (AD)-associated neuroinflammation[1].
Molecular Weight:
434.89
Purity:
98
CAS Number:
[2572552-60-2]
Formula:
C20H19ClN2O5S
Target:
Autophagy,Interleukin Related,mTOR
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
