XSJ110 is a potent irreversible topoisomerase I (Topo I) inhibitor with an IC50 value of 0.133 µM. XSJ110 blocks DNA topoisomerization, induces DNA double-strand breaks, and triggers cell cycle arrest at G0/G1 phase, inducing tumor cell apoptosis. XSJ110 is promising for research of ampullary carcinoma (AC)[1].
Molecular Weight:
404.42
CAS Number:
[203923-65-3]
Formula:
C23H20N2O5
Target:
Apoptosis,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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