INCB126503, CAS [[2640089-88-7]] Preis auf Anfrage
Catalog Number:
MCE-HY-174154
| Article Name: |
INCB126503, CAS [[2640089-88-7]] Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-174154 |
| Supplier Catalog Number: |
HY-174154 |
| Alternative Catalog Number: |
MCE-HY-174154-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| INCB126503 is an orally activeM, selective FGFR2/3 Inhibitor with IC50 values of 70 nM (FGFR1), 2.1 nM (FGFR2), 1.2 nM (FGFR3), 0.92 nM (FGFR3-V555L), 0.85 nM (FGFR3-V555M) and 64 nM (FGFR4). INCB126503 suppresses FGFR signaling in vivo without causing hyperphosphatemia and shows antitumor efficacy in xenograft models harboring FGFR3 genetic alterations[1]. |
| Molecular Weight: |
470.57 |
| CAS Number: |
[2640089-88-7] |
| Formula: |
C27H30N6O2 |
| Target: |
FGFR |
| Application Notes: |
MCE Product type: Reference compound |
