Amb929 (ZINC000002782982), a nsp3 ligand, is an anti-SARS-CoV-2 agent. Amb929 inhibits SARS-CoV2-mNG replication in VeroE6 cells with an EC50 of 34.7 µM. Amb929 has limited and moderate cytotoxicity for VeroE6 cells (CC50: 281 µM). Amb929 also inhibits SARS-CoV-2-mNG replication in Human Airway Epithelium (HAE)[1].
Molecular Weight:
513.61
CAS Number:
[438196-25-9]
Formula:
C29H27N3O4S
Target:
SARS-CoV
Application Notes:
MCE Product type: Reference compound
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