CPS-021 is a selective PAK4 PROTAC degrader with a DC50 of 50 nM. CPS-021 has potent antimigratory and invasive activity and significantly suppresses the invasion and metastasis of tumor cells in A549-luc lung metastasis mice model[1]. Pink: PAK4 ligand (HY-174822), Blue: CRBN ligase ligand (HY-10984), Black: linker
Molecular Weight:
954.13
Formula:
C52H63N11O7
Target:
Cadherin,PAK,PROTACs
Application Notes:
MCE Product type: Reference compound
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