ERK2-IN-6 (Compound 20) is a highly selective ERK1/2 inhibitor with an IC50 value of 7.9 nM for ERK2. ERK2-IN-6 inhibits the proliferation of BRAFV600E mutant cells (IC50=250 nM in A375 cells). ERK2-IN-6 is promising for research of solid tumors, such as BRAF-mutated melanoma[1].
Molecular Weight:
520.02
CAS Number:
[2095713-33-8]
Formula:
C28H30ClN5O3
Target:
ERK
Application Notes:
MCE Product type: Reference compound
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