GT-02216 can bind to GCase allosterically and enhance its activity. GT-02216 enhances the activity of GCase in primary human fibroblasts dose-dependently reduces the accumulation of its substrate, hexosylsphingosine (HexCer). GT-02216 reduces the Tau accumulation in mutant GBA1 fibroblasts. GT-02216 can be used for the study of Parkinsons disease[1].
Molecular Weight:
389.45
Purity:
98.91
CAS Number:
[2648407-76-3]
Formula:
C22H23N5O2
Target:
Glycosidase
Application Notes:
MCE Product type: Reference compound
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