mrt-5702D is a molecular glue degrader targeting cereblon (CRBN). mrt-5702D forms a CRBN-MRT-5702D-G3BP2 ternary complex to activate the ubiquitin-proteasome system for G3BP2 degradation. mrt-5702D is promising for research of G3BP2-related cancers (e.g., breast cancer, lung cancer) and neurodegenerative diseases[1].
Molecular Weight:
621.11
Formula:
C30H29ClN6O5S
Target:
Molecular Glues
Application Notes:
MCE Product type: Reference compound1
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