ELQ-453 is an inhibitor targeting the Qo site of the Plasmodium falciparum cytochrome bc1 complex (CytB) with an IC50 value of 0.57 nM. ELQ-453 blocks the mitochondrial function of the parasite, and suppresses Plasmodium infection in mosquitoes. ELQ-453 is promising for research of malaria[1].
Molecular Weight:
395.44
Formula:
C21H27F2NO4
Target:
Cytochrome P450,Parasite
Application Notes:
MCE Product type: Reference compound
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