Hsp90-Cdc37-IN-4, CAS [[2758818-41-4]] Preis auf Anfrage
Catalog Number:
MCE-HY-174347
| Article Name: |
Hsp90-Cdc37-IN-4, CAS [[2758818-41-4]] Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-174347 |
| Supplier Catalog Number: |
HY-174347 |
| Alternative Catalog Number: |
MCE-HY-174347-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| Hsp90-Cdc37-IN-4, a Celastrol (HY-13067) derivative, inhibits the Hsp90-Cdc37 protein-protein interaction (PPI). Hsp90-Cdc37-IN-4 selectively inhibits casein kinase 2 (CK2), reducing phosphorylation of its substrate Cdc37 at Serine 13. Hsp90-Cdc37-IN-4 induces G0/G1 cell cycle arrest and triggers apoptosis via the mitochondrial pathway. Hsp90-Cdc37-IN-4 demonstrates potent anti-breast cancer activity[1]. |
| Molecular Weight: |
638.84 |
| CAS Number: |
[2758818-41-4] |
| Formula: |
C40H50N2O5 |
| Target: |
Apoptosis,Casein Kinase,HSP |
| Application Notes: |
MCE Product type: Reference compound |