CK2-IN-15 (Compound Biv5) is a selective and potent bivalent protein kinase CK2 inhibitor with an IC50 value of 51 pM. CK2-IN-15 significantly reduces the replication of SARS-CoV-2 in HEK-ACE2-TMPRSS2 and Vero cells, and also reduces viral replication in an ex vivo model of human nasal epithelial cells. CK2-IN-15 is promising for research of beta-coronavirus infection-related diseases[1].
Molecular Weight:
567.12
Formula:
C34H35ClN4O2
Target:
Casein Kinase,SARS-CoV
Application Notes:
MCE Product type: Reference compound1
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