CYP51-IN-23-d3 is a potent and broad-spectrum CYP51 inhibitor with a MIC80 of 1 µg/mL against Aspergillus fumigatum. CYP51-IN-23-d3 can prevent fungal phase transformation and biofilm formation. CYP51-IN-23-d3 exhibits anti-drug resistance activity and fungal activity, and shows excellent safety for cells and significant pharmacological activity in mice. CYP51-IN-23-d3 can be used for the study of invasive fungal infections (IFIs)[1].
Molecular Weight:
629.51
Formula:
C29H27D3BrF2N7O2
Target:
Cytochrome P450,Fungal,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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