Clevidipine is a selective, short-acting L-type calcium channel antagonist with an IC50 of 7.1 nM. Clevidipine can competitively bind to calcium channels and exert rapid vasoselective vasodilation by blocking the influx of extracellular calcium ions, thereby reducing peripheral vascular resistance and effectively controlling acute severe hypertension. Clevidipine can also protect the myocardium from reperfusion injury by promoting the release of nitric oxide (NO). Clevidipine can be used in the research of acute hypertension, perioperative blood pressure management, and myocardial ischemia-reperfusion injury[1].
Molecular Weight:
456.32
Purity:
99.85
CAS Number:
[167221-71-8]
Formula:
C21H23Cl2NO6
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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