PROTAC PDE4 degrader-1, CAS [[3087311-36-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-174405
Supplier Catalog Number:
HY-174405
Alternative Catalog Number:
MCE-HY-174405-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PROTAC PDE4 degrader-1 (Compound 9m) is a selective and orally active PDE4 PROTAC degrader with a DC50 of 41.98 µM. PROTAC PDE4 degrader-1 potently inhibits the secretion of pro-inflammatory cytokines such as TNF-alpha and IL-6. PROTAC PDE4 degrader-1 significantly alleviates pulmonary inflammation in LPS (HY-D1056)-induced acute lung injury (ALI) mice Model[1]. Pink: PDE4 ligand (HY-174410), Blue: CRBN ligase ligand (HY-10984), Black: linker
