AChE-IN-90 (Compound 5b) is an orally active, brain-penetrant and potent acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.023 µM against human AChE and lower selectivity for butyrylcholinesterase (BuChE) (IC50 1.8 µM). AChE-IN-90 increases acetylcholine levels in the synaptic cleft. AChE-IN-90 is promising for research of neurodegenerative diseases such as Alzheimers disease[1].
Molecular Weight:
364.87
Formula:
C19H25ClN2O3
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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