Y040-7904 is a mitophagy activator. Y040-7904 enhances mitophagy by promoting mitochondria transport to autophagosomes and the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitophagy through the SIRT1/FoxO3 pathway. Y040-7904 upregulates the levels of Parkin, PINK1, and LC3II/I. Y040-7904 reduces amyloid-beta (Abeta) accumulation in both in vitro and in vivo models of Alzheimers disease[1].
Molecular Weight:
370.35
Purity:
99.36
CAS Number:
[889662-19-5]
Formula:
C20H18O7
Target:
Amyloid-beta,Mitophagy,PINK1/Parkin
Application Notes:
MCE Product type: Reference compound
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